MoxiSolv Injection (moxidectin) is a ready-to-use, sterile solution containing 1% moxidectin. Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. MoxiSolv Injection is specially formulated to allow moxidectin to be absorbed from the site of injection and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. Moxidectin binds selectively and with high affinity to glutamate-gated chloride ion channels which are critical to the function of invertebrate nerve and muscle cells. This interferes with neurotransmission resulting in paralysis and elimination of the parasite.

MoxiSolv Injection, when administered at the recommended dose level of 0.2 mg/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle:

Gastrointestinal Roundworms: Ostertagia ostertagi - adults and L4 (including inhibited Larvae), Haemonchus placei - adults, Trichostrongylus axei – adults and L4, Trichostrongylus colubriformis – adults and L4, Cooperia oncophora – adults, Cooperia punctata – adults and L4, Cooperia pectinata - adults, Cooperia spatulata - adults, Cooperia surnabada – adults and L4, Nematodirus helevtianus - adults, Oesophagostomum radiatum – adults and L4, Trichuris spp. - adults

Lungworms: Dictyocaulus viviparus – adults and L4

Cattle Grubs: Hypoderma bovis, Hypoderma lineatum

Mites: Psoroptes ovis (Psoroptes communis var. bovis)

Sucking Lice: Linognathus vituli, Solenopotes capillatus